Fri Oct 17 2025

128 articles - From Friday Oct 10 2025 to Friday Oct 17 2025

parm_toc.knit

Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…

Endosc Int Open
Retrospective accuracy analysis of major guidelines and factors for lymph node metastasis of pT1 colorectal cancer.

HDG, LVI, TB, and gender (female) are independent risk factors for LNM of T1 CRC. DSI is an excellent negative predictor, although not an independent risk factor. The NCCN/ESMO guideline has medium sensitivity and requires improvement. The JSCCR/FICPG guideline has perfect sensitivity but low specificity, thus exposing patients to many unnecessary surgeries. There is revision potential for current guideline factors, including those beyond current pathological ones, to improve LNM prediction accuracy.

Pubmed   Journal   ReadQx   PMC

Endoscopy
Time trends in post-polypectomy surveillance guideline adherence: analysis of over 90 000 colonoscopies with polypectomy.

An improvement of up to 49% in ESGE guideline adherence was observed over 4 years after publication of the update, which was mostly driven by improved adherence to the surveillance intervals for adenomas. Endoscopists with higher ADRs were more likely to assign correct follow-up intervals.

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J Hepatol
Consensus position statements for the standardized application of histological grading and staging systems in MASH clinical trials.

The IMPG statements provide for the first time guidelines to promote consensus among liver pathologists for the histopathological evaluation and scoring of liver biopsies for MASH clinical trials. Furthermore, they may be used to inform supervised machine learning algorithms for quantitative MASLD histology assessments. Impact and implications Inter- (and intra-) observer variations in the histological interpretation of key morphological features of MASH limit the precision of histological grading and staging as well as the diagnosis of the histological MASLD types, MASL and MASH. This is thought to account in clinical trials, at least in part, for screening failure as well as variable placebo response rates, potentially obscuring treatment effects. The International MASLD Pathology Group, consisting of 25 expert liver pathologists, generated consensus statements for histopathological procedures, technical aspects and histological criteria for the diagnosis of MASH, for grading disease activity and staging fibrosis. These may provide a basis for standardized histologic interpretation and the development of AI-based grading and staging algorithms for clinical trials of MASH.

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J Neurogastroenterol Motil
Treatment of Irritable Bowel Syndrome With Antispasmolytics in Taiwan, Hong Kong, and Vietnam: A Delphi Expert Consensus Statement.

Although antispasmolytics provide immediate symptom relief, their long-term effectiveness needs further investigations in Asian populations. Our findings may inform clinical decision-making and guideline updates.

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Meta-analysis

meta-analyses and systematic reviews

Aliment Pharmacol Ther
Meta-Analysis: Efficacy and Safety of Sequestrants for Bile Acid Diarrhoea.

This study quantifies the significant and rapid improvement in both stool consistency and frequency with BAS in patients with objective diagnosis of bile acid diarrhoea. Sequestrants also appear well tolerated.

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Meta-Analysis: Utilisation of Hepatocellular Carcinoma Surveillance.

Less than 10% of patients received the recommended biannual ultrasound scans for surveillance. These findings are concerning and call for greater awareness and collaboration between care providers and healthcare policymakers to improve surveillance utilisation.

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Clin Gastroenterol Hepatol
Non-Invasive Prediction Models of First Decompensation in Compensated Advanced Chronic Liver Disease - A Meta-Analysis.

CACLD specific NITs offer the best option in predicting decompensation, and future studies should focus on robust validation, calibration and external validation with standardised endpoints to ensure that models are reliable for guiding clinical practice in applicable populations.

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Placebo Rates in Metabolic Dysfunction-associated Steatohepatitis Clinical Trials: A Systematic Review and Meta-analysis.

Placebo response rates among patients with MASH are generally elevated yet vary considerably depending on the outcome measured. This study provides valuable insights to enhance the design of future MASH trials.

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Gastrointest Endosc
Clinical Impact of Routine Esophagram after Peroral Endoscopic Myotomy: A Systematic Review and Meta-analysis.

Esophageal leakage is a very uncommon AE after POEM. Routine esophagram rarely impacted immediate post-procedural care in asymptomatic patients. Selective imaging may result in higher diagnostic yield, improved cost-efficiency, and mitigate the risk of unwarranted additional testing due to incidental radiographic findings.

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Underwater vs Traction-assisted ESD in Colorectal Lesions Underwater versus Traction-assisted Endoscopic Submucosal Dissection for Colorectal Lesions: A Network Meta-Analysis of Randomized Controlled Trials.

UW-ESD and T-ESD are both effective and safe strategies for colorectal lesions resection; however, UW-ESD is the only technique that has demonstrated superior dissection speed.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Aliment Pharmacol Ther
Biomarkers of Extracellular Matrix Remodelling Are Linked to Severity and Outcome of Advanced Chronic Liver Disease.

ECM remodelling biomarkers reflect PH and disease severity in ACLD. Their prognostic value for disease progression is largely restricted to cACLD. Future studies should investigate whether repeated measurements improve risk stratification.

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Clinical Trial: Rifaximin Versus Low FODMAP Diet in Irritable Bowel Syndrome.

Rifaximin is as effective as LFD in treating IBS over 4 weeks. However, it provides faster symptom relief and higher treatment adherence, making it a practical alternative for symptom management.

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Mild Endoscopic Disease Activity Is Associated With Adverse Outcomes Among Older Adults With Inflammatory Bowel Disease.

Among older adults with prevalent IBD, mild endoscopic disease activity, as compared to endoscopic remission, was associated with increased odds of adverse IBD-specific and morbidity-related outcomes at 1 year, with this risk persisting for IBD-specific outcomes at 5 years. These findings highlight the importance of achieving endoscopic remission, which may confer both short- and longer-term benefits in this population.

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Overall and Comparative Risk of Shingles With Advanced Therapies in Patients With Inflammatory Bowel Diseases.

JAK inhibitors were associated with 1.7-2.2-fold higher risk of shingles than other advanced therapies.

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Research Communication: An Observational Cohort Study on Risk of Ovarian Cancer in Women with Irritable Bowel Syndrome.

Some women with symptoms of ovarian cancer may be misdiagnosed with IBS, although IBS is not causally linked to ovarian cancer. Further studies are needed to validate findings and clarify when ovarian cancer screening may be warranted.

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Research Communication: Comparative Effectiveness of Ustekinumab and Vedolizumab in the Management of Chronic Pouchitis-A Population-Based Study.

Our findings suggest that ustekinumab may offer advantages over vedolizumab in the management of chronic pouchitis.

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Research Communication: Prevalence of Asymptomatic Premalignant Oesophageal Lesions in Patients With Fanconi Anaemia.

Among 11 FA patients with abnormal oesophageal mucosa, 15% had low-grade dysplasia, nodular high-grade dysplasia or squamous carcinoma in situ, 10% had non-dysplastic Barrett's oesophagus and 30% had columnar epithelium without goblet cells, compared to none in the controls (p < 0.001). Our findings support routine EGD screening of asymptomatic FA patients.

Pubmed   Journal   ReadQx   PMC

Social Determinants of Health in Metabolic Dysfunction-Associated Steatotic Liver Disease and All-Cause/Cause-Specific Mortality.

This US population-based study demonstrates that SDoH scores are dose-dependently associated with increased all-cause/cause-specific mortality among individuals with MASLD.

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Am J Gastroenterol
An organized fecal immunochemical test-based screening program impacts colorectal cancer early diagnosis and survival in the short term.

Biennial FIT led to an increase in early diagnoses and improved survival, compared to no screening, in the short term after its introduction. A screening program that includes alternatives to FIT may increase population coverage and improve CRC outcomes.

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Assessing the reliability of 12 vs 24 hour esophageal pH-impedance monitoring for gastro-esophageal reflux in infants.

Each MII-pH was analyzed twice as full-time recording and in the first 12h, and data were compared. GERD was diagnosed if one of the following occurred: Number of GER episodes ≥100 in 24 hours; proximal GER episodes >44 (acid) or 57 (non-acid); Reflux index (percent time with pH 5 minutes were significantly different between the two, but the clinical significance of this observation is unclear.

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Delayed Remission With Advanced Therapies Is Not Associated With Worse One-Year Outcomes In Inflammatory Bowel Disease.

About one-sixth of patients achieved delayed remission by week 30. They had comparable one-year outcomes as early remitters. Identifying predictors of delayed remission could help prevent early therapy discontinuation without affecting long-term outcomes.

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One versus five days of octreotide infusion for acute esophageal variceal bleeding: a randomized controlled trial.

Following successful endoscopic band ligation, the 1-day regimen of octreotide had a non-inferior effect compared to the standard 5-day regimen in the prevention of 5-day re-bleeding and exhibited no significant differences in the prevention of 6-week re-bleeding and all-cause mortality.

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SAFETY AND EFFICACY OF PNEUMATIC BALLOON DILATION FOR PEDIATRIC ACHALASIA - A SINGLE-CENTER EXPERIENCE.

PD is a safe, effective first-line treatment for pediatric achalasia.

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Validation of Dried Blood Spot Immunoreactive Trypsinogen (DBS-IRT) as a Biomarker of Exocrine Pancreas Function in Children with Pancreas Disease.

DBS-IRT was successfully validated as a biomarker of exocrine pancreas function which allows its use in clinical setting, in addition to fecal elastase to determine pancreas function.

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Vonoprazan Improves Nocturnal Gastroesophageal Reflux Symptoms in Non-Erosive Reflux Disease.

Our study suggests that vonoprazan leads to relief of nighttime heartburn in patients with heartburn and a normal endoscopy.

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Clin Gastroenterol Hepatol
AI-ASSISTED CAPSULE ENDOSCOPY FOR DETECTION OF ULCERS AND EROSIONS IN CROHN'S DISEASE: A MULTICENTER VALIDATION STUDY.

The AI-assisted SBCE reading achieved superior diagnostic performance compared to SoC, with a substantial decrease in reading time.

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Changes in HBcAg and HBsAg Expression Following Antiviral Therapy and Their Role in Outcome of Patients with Chronic Hepatitis B.

NA-related inhibition of viral replication was associated with marked reduction in HBcAg expression in HBeAg-positive and HBeAg-negative patients but minimal changes in extent of HBsAg staining, likely reflecting HBsAg production from integrated HBV DNA.

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Experienced Discrimination and Medical Mistrust Among Patients with Cirrhosis: Survey Results from a Multicenter Cohort.

Experienced discrimination and medical mistrust are common among Black patients with cirrhosis. Addressing these factors may mitigate racial and ethnic inequities in care, reduce barriers to care and improve outcomes for patients with cirrhosis.

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From Pixels to Peristalsis: Comparing Achalasia Diagnosis with Artificial Intelligence to Expert Endoscopists.

These results indicate that AI can leverage upper endoscopy videos to detect achalasia with an accuracy comparable to that of expert endoscopists.

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Long-Term Glycemic Control and the Risk of Liver Stiffness Progression and Liver-Related Events in MASLD.

T2D was independently associated with a higher risk of liver stiffness progression and LRE in MASLD. Good glycemic control was associated with slower liver stiffness progression, but not regression or LRE.

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Long-term safety of vedolizumab in patients with ulcerative colitis/Crohn's disease: A prospective observational study.

There was no new safety signal identified in relation to vedolizumab. Results regarding safety and effectiveness were consistent with the known profile of vedolizumab.

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Seroprevalence of Helicobacter pylori infection among asymptomatic patients served by a safety-net healthcare system.

In this population-based study, almost two-thirds of asymptomatic patients were seropositive for H. pylori. Prevalence was over 40% among al sub-groups. Screening solely based on race and ethnicity may inadvertently exacerbate disparities by overlooking confounding factors for infection like low socioeconomic status and regional exposures.

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Endosc Int Open
Endoscopic indigo carmine spraying for evaluation of intestinal mucosal permeability: Prospective pilot study.

Endoscopic spraying with IC is useful for evaluation of intestinal mucosal permeability.

Pubmed   Journal   ReadQx   PMC

Impact of interaction between an artificial intelligence endoscopic support system and endoscopists on diagnosis of gastric neoplastic lesions.

AI contributed to improved diagnostic performance even among Japanese expert endoscopists in detecting gastric neoplastic lesions. These findings suggest that the AI system may have potential to support consistently high diagnostic performance across varying levels of endoscopic expertise.

Pubmed   Journal   ReadQx   PMC

Large language model for interpreting the Paris classification of colorectal polyps.

M-LLMs performed comparably to endoscopists in distinguishing non-polypoid from polypoid lesions but failed to reliably identify pedunculated morphology.

Pubmed   Journal   ReadQx   PMC

Endoscopy
A Prospective Study Evaluating an Artificial Intelligence-Based System for Withdrawal Time Measurement.

Our study demonstrates the superiority of an AI system in calculating WT during colonoscopy compared to physicians, providing significant improvements, especially in examinations containing interventions. This work demonstrates the promise of AI in streamlining clinical workflows.

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A Rural-to-Center Artificial Intelligence Model for Diagnosing Helicobacter pylori Infection and Premalignant Gastric Conditions Using Endoscopy Images Captured in Routine Practice.

AI enables frontline physicians in resource-limited settings to rapidly assess gastric health using routinely captured endoscopic images, bridging gaps in access and expertise (ClinicalTrials.gov NCT05762991).

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Delayed post-polypectomy bleeding following cold snare polypectomy of lesions <10 mm in patients on high-dose antithrombotic therapy: insights from a Dutch colonoscopy cohort.

Although higher compared to patients without ATT, the incidence of DPPBs with continued high-dose ATT remains very low. Therefore, we suggest continuation of high-dose ATT for colonoscopy indications with a low risk of detecting advanced polyps.

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Endoscopic papillectomy for ampullary lesions: pooled analysis with meta-regression analysis of outcomes.

Endoscopic papillectomy is a safe and effective treatment for ampullary lesions. However, lesions with intraductal extension pose a higher risk of incomplete resection and perforation, warranting careful evaluation of the benefit-risk balance in these cases.While prophylactic pancreatic stenting may reduce the incidence of post-procedural pancreatitis, optimizing strategies to minimize overall adverse events remains a key focus for future research.

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Endoscopic ultrasound-guided trans-papillary versus trans-luminal biliary stenting: Randomized comparison of long term stent patency.

EUS-BD via TP route achieved longer stent patency and lower rate of recurrent biliary obstruction at 3 and 6 months compared to TL route.

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Impact of prophylactic clipping on delayed bleeding after colorectal endoscopic submucosal dissection: a multicenter propensity score-matched study.

In our cohort, prophylactic clipping did not significantly reduce CSDB following colorectal ESD, even in high-risk patients. Given its environmental impact and technical challenges, routine closure should be reconsidered.

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Gastrointest Endosc
Cystic Fibrosis Carrier Status: A genetic predisposition to post-ERCP pancreatitis.

CFC status appears to increase predisposition to PEP, highlighting the potential for improved pre-procedural risk assessment and prophylaxis and opportunities for further study to identify novel PEP prophylactic strategies.

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Lumen-Apposing Metal Stents for Partial Reversal of Roux-en-Y Gastric Bypass: A Multicenter Study.

EUS-guided LAMS placement is a safe, efficacious and minimally invasive strategy for partial reversal of RYGB as either a bridge to definitive surgical reversal or as destination therapy.

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Randomized Controlled Trial Comparing the Clinical Efficacy of a Bipolar Current Knife versus Monopolar Current Knife During Esophageal PerOral Endoscopic Myotomy: A Multicenter Non-inferiority Study.

77% of patients in BC completed the entire procedure with one instrument vs none in MC. Only one major adverse event occurred in BC (managed endoscopically) (1.9%) CONCLUSION: The 3-in-1 function of a novel bipolar RFA knife can facilitate POEM with one device.

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Sequential Lumen-Apposing Metal Stent and Septotomy Technique for Endoscopic Anastomosis Creation and Revision in Patients with Prior Upper Gastrointestinal Surgery.

Our technique is safe, effective, and feasible for durable endoscopic anastomosis creation or revision in appropriately selected patients with prior upper GI surgery.

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The Effect of Autonomous Mobile Robots on Improving Endoscope Reprocessing Efficiency: A Prospective Comparative Trial.

AMR-assisted endoscope delivery has advantages over manual delivery in efficiency improvement, offering a novel solution for the management of endoscopy centers.

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Transenteric ERCP via EUS-guided anastomosis using LAMS in patients with surgically altered anatomy.

The EDEE technique offers a new and effective approach for biliary drainage in patients with surgically altered anatomy, particularly in benign indications and/or when several ERCPs are expected.

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Gut
KIF1Bβ suppresses hepatocellular carcinoma by transporting and secreting FBLN5 to attenuate the integrin pathway.

Our findings shed light on the genetic and molecular mechanisms of the HCC-associated susceptibility locus at 1p36.22 and provide potential new strategies for the treatment of HCC.

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Long-term prognosis of lean MASLD: evidence from three population-based prospective cohorts.

Lean patients with MASLD have worse liver outcomes and greater risk of all-cause mortality, but similar risk of HCC and extrahepatic cancer, and lower CVD risk.

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Rectal versus colonic submucosal cancer rates and procedural outcomes in large non-pedunculated polyps: French ESD registry data.

In our multicentre registry, large non-pedunculated polyps do not show a higher prevalence of SMIC in the rectum compared with colon, when adjusted for relevant factors such as size and morphology. Therefore, risk features, rather than location, should guide the choice of resection technique. Technical outcomes were comparable between rectal and colonic ESD, with a trend for higher complication rates in the colon.

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Hepatology
Global performance of non-invasive tests in MASLD: Insights from the G-MASLD study.

Diagnostic performance of common non-invasive tests for fibrosis in MASLD varies across the world. In the large multinational G-MASLD sample, the most accurate NITs were Agile-3+ and Agile-4 composite scores.

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Hepatocyte-derived extracellular vesicles promote endothelial dedifferentiation in chronic liver disease through the miR-153-3p - pyroptosis axis.

HepEVs-derived miRNAs, particularly miR-153-3p, contribute to endothelial dysfunction in CLD by triggering pyroptosis through a paracrine mechanism. Inhibiting Caspase-1 may provide a novel therapeutic approach to mitigate endothelial dysfunction in CLD.

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MSR1+ macrophages passivate antitumor immunity by inducing ITM2A+ CD4T exhaustion differentiation.

MSR1+macrophages promote tumor-infiltrating ITM2A+CD4T exhaustion differentiation by regulating the ITM2A-ZAP70 axis. ZEA-αCD4 specifically targeted MSR1-ITM2A interaction to activate antitumor immunity and improve the efficacy of αPDL1 immunotherapy.

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Reclassifying pediatric NAFLD using the steatotic liver disease framework: a multicenter retrospective study from the NASH CRN.

Most children with NAFLD met MASLD criteria, but nearly 1 in 6 were reclassified based on alcohol use or medication exposure. These findings highlight the need for a systematic diagnostic approach accounting for metabolic risk factors, alcohol use, and medication-related liver injury.

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Sex and body size disparities under MELD 3.0: Evaluation of persisting gaps in liver transplant access.

MELD3.0 led to early gains in transplant access for women, though this effect diminished over time and differences by sex mediated by body size persisted.

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J Hepatol
Early portopulmonary hypertension predicts mortality in patients with cirrhosis: insights from the PORTO-DETECT cohort.

Applying the 2022 ESC/ERC definitions of PAH identifies a subset of patients with cirrhosis with early-stage PoPH, characterized by mild pulmonary vascular resistance elevation, who nevertheless face a markedly increased risk of death, emphasizing the need for systematic screening and early targeted intervention. Impact and implications Portopulmonary hypertension (PoPH) is a severe and often overlooked complication of cirrhosis. Using the updated 2022 ESC/ERS diagnostic criteria, this multicenter study identified a previously unrecognized subgroup of cirrhotic patients with early-stage PoPH, defined by mildly elevated pulmonary vascular resistance and mean pulmonary artery pressure. Despite their subtle hemodynamic changes, these patients showed significantly reduced survival, independent of liver disease severity. These results highlight the prognostic relevance of early PoPH and suggest that applying the new criteria may help refine risk stratification and guide closer follow-up or earlier consideration of targeted interventions in selected patients.

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Genetically engineered pig-to-human liver xenotransplantation.

This study demonstrates the feasibility of auxiliary porcine liver xenotransplantation as a bridging approach to human to liver transplantation. Postoperative xTMA presents a significant challenge to long-term success, highlighting the need for further research to improve xenotransplantation outcomes. Impact and implications This study reports the world's first auxiliary xenotransplantation from a 10-gene-edited pig to a living human recipient - distinct from previous studies involving brain-dead donors. The donor liver was engineered using a 10-gene editing platform, including the knockout of xenoantigen genes and the knock-in of seven human transgenes for immune and coagulation compatibility - pushing the boundaries of synthetic biology in clinical transplantation. The porcine graft exhibited metabolically active liver function, bile secretion, and coagulation correction, demonstrating not only survival but clinically meaningful function. Our work documents, for the first time, xenotransplantation-associated thrombotic microangiopathy (xTMA) in a living human recipient, with comprehensive immunological and histopathological analysis - critical knowledge for the field.

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J Neurogastroenterol Motil
Age- and Sex-dependent Effects of High-fructose, High-fat Diets on Small Bowel Inflammation and Hepatic Steatosis in F344 Rats.

Liver and small bowel tissues were histologically analyzed. Tight junction protein expression in jejunal mucosa was analyzed, and immunohistochemistry was performed to detect claudin-2 ( may contribute to MASLD in aged female rats.

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Can Symptoms Predict Delayed Gastric Emptying in Diabetic Patients: A Multicenter Study to Revisit Gastroparesis.

Diabetic patients exhibiting specific cardinal symptoms should be considered for GES evaluation, as the overall GCSI score independently predicts delayed gastric emptying. This study suggests that the GCSI may be useful as a screening tool rather than a diagnostic method for diabetic gastroparesis.

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Comparison of Clinical Characteristics and Long-term Prognosis of Focal Hypoganglionosis With Adult-onset Megacolon and Chronic Intestinal Pseudo-obstruction.

Patients with FHAM exhibit a more favorable long-term prognosis and lower postoperative recurrence rates than patients with CIPO. This study underscores the importance of differentiating between these conditions and precisely selecting surgical candidates.

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Diagnosis of Sliding Hiatal Hernia in Patients With Morbid Obesity: A Comparison of High-resolution Esophageal Manometry and Upper Gastrointestinal Series.

HREM has high diagnostic performance in detecting sliding HH; thus, HREM should be considered as an important part of the preoperative work-up for patients with morbid obesity.

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Impact of Enhanced Dietary Education Program on Gastrointestinal Symptoms in Patients With Functional Gastrointestinal Disorders: A Multicenter Prospective Pilot Study.

Although, EDE has the potential to help improving the symptoms in patients with FGIDs, further research is needed to prove the usefulness of this program.

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Predictors of Treatment Response to Fecal Microbiota Transplantation in Irritable Bowel Syndrome: A Pilot Study.

FMT led to increased microbial diversity and a sustained increase in beneficial bacterial genera, including and greater shifts of gut microbiome profile toward donor microbiota after FMT may predict favorable FMT response. Long-term follow-up is on the way to assessing the durability of these effects.

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The Effect of Tegoprazan on Serum Gastrin Levels and the Development of Hypergastrinemia in the Maintenance Treatment for Gastroesophageal Reflux Disease: Comparison to Lansoprazole.

Tegoprazan has a smaller impact on increasing serum gastrin levels and the development of hypergastrinemia than lansoprazole, suggesting that tegoprazan may reduce safety concerns related to hypergastrinemia, particularly at half doses.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Aliment Pharmacol Ther
Editorial: Advancing HCC Surveillance in Hepatitis B With Biomarker-Based Strategy.

Pubmed   Journal   ReadQx 

Editorial: Immune Checkpoint Inhibitors and HBV Reactivation in Liver Cancer-Reassurance With Vigilance.

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Editorial: Predicting Hepatocellular Carcinoma Development in Chronic Hepatitis B Patients With Metabolic Dysfunction-Do Existing Scores Clear the Bar?

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Clin Gastroenterol Hepatol
Metabolic comorbidities accelerate liver fibrosis in chronic hepatitis B - time to act.

Pubmed   Journal   ReadQx 

J Hepatol
Alcohol consumption potentiates second-hit events in HBV-induced hepatocellular carcinoma.

Pubmed   Journal   ReadQx 

Bioartificial Liver System for Liver Failure: A Therapeutic UTOpiA on the Horizon.

Pubmed   Journal   ReadQx 

Measuring Health Related Quality of Life and Patient-Reported Outcomes in Chronic Liver Disease.

We review the current literature on CLD symptom burden and its relationship with PROs concluding that PRO measurement incorporation into clinical trials and clinical practice is imperative to appreciate patients' perspectives about their liver disease and/or its treatment. PROs enhance communication between healthcare providers and patients regarding treatment expectations potentially improving outcomes.

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The first human xenogeneic liver transplantation - A landmark event, but what does it mean for hepatology?

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J Neurogastroenterol Motil
Implementing a Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols Diet in Asia: Addressing Cultural, Clinical and Practical Challenges.

Potential solutions include building local capacity in dietary research and clinical practice; expanding the analysis of Asian foods for FODMAP content; fostering interdisciplinary training opportunities for health professionals using a train-the-trainer approach; adapting educational resources so they are linguistically and culturally appropriate; and developing practical resources for patients to facilitate recipe adaptation and meal planning. Addressing these barriers will improve access to the FODMAP diet for patients in Asia and may provide a framework to adapt other dietary therapies to suit culturally diverse groups.

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Insights Into Functional Dyspepsia and Gastroparesis - Western Versus Asian Perspectives.

These differences stem from varying accessibility to investigation tests and medications, dietary habits and cultural beliefs. This review article comprehensively summarizes the latest knowledge on the approach to the evaluation and management of functional dyspepsia and gastroparesis, and explores the different factors influencing management practices in the West as compared to in Asia.

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Is Fecal Microbiota Transplantation Applicable for the Treatment of Irritable Bowel Syndrome? Time for Precision Medicine.

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The Need for Objective Testing in Proton Pump Inhibitor-refractory Extraesophageal Gastroesophageal Reflux Disease.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Am J Gastroenterol
How I Approach Flatulence.

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Letter to the Editor.

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The Illusion of Response: Diffuse Hepatic Metastasis Masked by Shrinking Lesions in Neuroendocrine Carcinoma of the Cervix.

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Clin Gastroenterol Hepatol
Capsule Endoscopy in Chronic Mesenteric Ischemia Before and After Revascularization.

Pubmed   Journal   ReadQx 

Diaphragmatic ectopic variceal bleeding secondary to chronic primary idiopathic Budd-Chiari syndrome.

Pubmed   Journal   ReadQx 

Impact of Social Determinants of Health on Hepatocellular Carcinoma Surveillance Receipt and Early Detection.

Pubmed   Journal   ReadQx 

Lymphoepithelial Cyst of the Cervical Esophagus with Distinct Endoscopic Ultrasonography Findings.

Pubmed   Journal   ReadQx 

Measles Outbreaks 2025 and Beyond: Implications for Immunosuppressed Patients Managed by Gastroenterologists and Hepatologists.

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Endosc Int Open
Endoscopic management of a sessile serrated lesion at the appendiceal orifice.

Pubmed   Journal   ReadQx   PMC

Endoscopy
Circumferential long-segment Barrett's esophagus fully involved by adenocarcinoma resected by endoscopic submucosal dissection.

Pubmed   Journal   ReadQx   PMC

Duodenal endoscopic submucosal dissection using dual-channel rapid hemostasis for a large tumor involving the papilla.

Pubmed   Journal   ReadQx   PMC

Endoscopic laser lithotripsy for an impacted pancreatic duct stone using a novel ultra-slim cholangiopancreatoscope via the minor papilla.

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Endoscopic submucosal dissection using a novel multi traction device.

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Endoscopic ultrasonography-guided removal of a migrated stent from the abdominal cavity after transgastric endoscopic ultrasonography-guided drainage of a biliary leak.

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Endoscopic ultrasound-guided radiofrequency ablation for a pancreatic insulinoma: a novel endoscopic management strategy.

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Gastrointest Endosc
Double-balloon enteroscope assisted endoscopic sigmoidocecoanastomosis in a patient with intestinal pseudoobstruction.

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Gastric peroral endoscopic myotomy for gastric remnant volvulus-associated pseudo-pyloric stenosis after esophagogastrostomy.

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Innovative pulley traction technique for esophageal ESD using endoclips and fishing line.

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Lumen-apposing metal stent used to facilitate gastric band retrieval in a patient with a vertical band gastroplasty.

Pubmed   Journal   ReadQx 

Novel self-made multi-loop dental floss traction device for enhanced endoscopic submucosal dissection in the gastric body.

Pubmed   Journal   ReadQx 

Hepatology
Bundle it up-Care bundles for spontaneous bacterial peritonitis.

Pubmed   Journal   ReadQx 

Fellows' Corner.

Pubmed   Journal   ReadQx 

Letter to the Editor: Methodological refinements needed in assessing Metabolic-Viral fibrosis interactions.

Pubmed   Journal   ReadQx 

Letter to the Editor: Re-evaluating the clinical relevance of the RIPPLY1-TBX19 Axis in CTNNB1-Mutant hepatocellular carcinoma.

Pubmed   Journal   ReadQx 

Letter to the editor: Esophageal varices in Fontan patients - circulatory or hepatic failure?

Pubmed   Journal   ReadQx 

Reply: HBV DNA level of genuine immune-tolerant patients.

Pubmed   Journal   ReadQx 

Reply: Methodological refinements needed in assessing metabolic-viral fibrosis interactions.

Pubmed   Journal   ReadQx 

Surgical resection for hepatocellular carcinoma: Leave no TACE?

Pubmed   Journal   ReadQx 

Time to focus on POCUS For AKI management in cirrhosis.

Pubmed   Journal   ReadQx 

When "remission" isn't enough: The unseen burden of autoimmune hepatitis.

Pubmed   Journal   ReadQx 

Who improves, who doesn't and why? Defining improvement and drivers of outcomes in pediatric MASLD.

Pubmed   Journal   ReadQx 


Letters&Replies

Letters to the editors and authors’ replies

Aliment Pharmacol Ther
Editorial: Advancing HCC Surveillance in Hepatitis B With Biomarker-Based Strategy-Authors' Reply.

Pubmed   Journal   ReadQx 

Editorial: Immune Checkpoint Inhibitors and HBV Reactivation in Liver Cancer-Reassurance With Vigilance. Authors' Reply.

Pubmed   Journal   ReadQx 

Editorial: Predicting Hepatocellular Carcinoma Development in Chronic Hepatitis B Patients With Metabolic Dysfunction-Do Existing Scores Clear the Bar? Authors' Reply.

Pubmed   Journal   ReadQx 

Letter Regarding 'Combined Lyon and Milan Scores Predict Gerd Management Outcome Better Than Either Score Alone or Their Individual Components'.

Pubmed   Journal   ReadQx 

Letter Regarding 'Combined Lyon and Milan Scores Predict Gerd Management Outcome Better Than Either Score Alone or Their Individual Components'. Authors' Reply.

Pubmed   Journal   ReadQx 

Letter on "Efficacy and Safety of Tenofovir Alafenamide (TAF) and Tenofovir Disoproxil Fumarate (TDF) Followed by TAF in Chronic Hepatitis B Patients of East Asian Ethnicity Following 5 Years of Treatment".

Pubmed   Journal   ReadQx 

Letter: Gas-Sensing Capsules Advance Colonic Physiology Research Toward Clinical Translation.

Pubmed   Journal   ReadQx 

Letter: Gas-Sensing Capsules Advance Colonic Physiology Research Toward Clinical Translation. Authors' Reply.

Pubmed   Journal   ReadQx 

Letter: Methodological Flaws and Clinical Gaps-A Critique of TAF/TDF 5-Year Data in East Asian CHB.

Pubmed   Journal   ReadQx 

Letters on "Efficacy and Safety of Tenofovir Alafenamide (TAF) and Tenofovir Disoproxil Fumarate (TDF) Followed by TAF in Chronic Hepatitis B Patients of East Asian Ethnicity Following 5 Years of Treatment." Authors' Reply.

Pubmed   Journal   ReadQx 

Gastroenterology
Advancing Patient Care with the GRAVITI Trial.

Pubmed   Journal   ReadQx 

GRAVITI Study on Guselkumab's Efficacy and Safety for Moderate to Severe Crohn's Disease.

Pubmed   Journal   ReadQx 

Reevaluating the GRAVITI Trial of Subcutaneous Guselkumab for Crohn's Disease.

Pubmed   Journal   ReadQx 

Subcutaneous IL-23 Blockade as a Patient-Centered Strategy in Crohn's Disease.

Pubmed   Journal   ReadQx 

Gut
Response to: 'Cutting waste in endoscopy: the roles of professional practice and staffing levels' by Fujisawa and Fujikawa.

Pubmed   Journal   ReadQx 

Response to: 'Lumen-apposing metal stents for pancreatic fluid collections: has advancing technology encouraged overreach?' by Besim Fazil <i>et al</i>.

Pubmed   Journal   ReadQx 

J Hepatol
Can Autoimmune Hepatitis be diagnosed and treated without liver biopsy?

Pubmed   Journal   ReadQx 

Comment on "Risk of alcohol-related liver disease and cause-specific mortality in individuals seeking treatment for alcohol use disorder".

Pubmed   Journal   ReadQx 

Primary prophylaxis of spontaneous bacterial peritonitis using rifaximin in patients with severe cirrhosis and ascites, not the end of the story?

Pubmed   Journal   ReadQx 

Striking Elevation of Alpha- Fetoprotein During Acute Transient Myopathy Following Yttrium-90 Trans-Arterial Radioembolization.

Pubmed   Journal   ReadQx 

J Neurogastroenterol Motil
Behavioral Postprandial Distress in Autism Spectrum Disorder: Behavioral Clues Beyond Physiology.

Pubmed   Journal   ReadQx